Home teams are listed in bold and the match winners are GREEN.
Click on completed matches to view score sheet.
| Week 1 - 09/16/2021 | Lady Hawks (1) at 50 KILLERS (5) |
| Week 2 - 09/23/2021 | Trump Train "Choo Choo" (6) at LADY HAWKS (0) |
| Week 3 - 09/30/2021 | Lady Hawks at BYE |
| Week 4 - 10/07/2021 | Lady Hawks (0) at DEAD STROKE (6) |
| Week 5 - 10/14/2021 | Anustart (5) at LADY HAWKS (1) |
| Week 6 - 10/21/2021 | Lady Hawks (0) at PHAT KATS (6) |
| Week 7 - 10/28/2021 | Scratch It (5) at LADY HAWKS (1) |
| Week 8 - 11/04/2021 | 50 Killers (3) at LADY HAWKS (3) |
| Week 9 - 11/11/2021 | Lady Hawks (2) at TRUMP TRAIN "CHOO CHOO" (4) |
| Week 10 - 11/18/2021 | BYE at LADY HAWKS |
| Week 11 - 12/02/2021 | Dead Stroke (5) at LADY HAWKS (1) |
| Week 12 - 12/09/2021 | Lady Hawks (0) at ANUSTART (6) |
| Week 13 - 12/16/2021 | Phat Kats (6) at LADY HAWKS (0) |
| Week 14 - 12/23/2021 | Lady Hawks (0) at SCRATCH IT (6) |
| Week 15 - 12/30/2021 | Lady Hawks at 50 KILLERS |
| Week 16 - 01/06/2022 | at PLAYOFFS |